The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 954220-98-5, name is 2,4-Dichloro-5-fluoro-6-methylpyrimidine. This compound has unique chemical properties. The synthetic route is as follows. SDS of cas: 954220-98-5
Step 2 To 28 (25 g, 138 mmol) in THF (250 mL) at 0 C was added 30 g of a 25%/wt NaO e in methanol solution (138 mmol). Allowed to warm to room temperature over 30 minutes. Concentrated the reaction in vacuo. Purified the residue by silica gel chromatography (0-20% acetone/hexane over 20 minutes) to provide 29 (12. 6 g, 52%).
With the rapid development of chemical substances, we look forward to future research findings about 954220-98-5.
Reference:
Patent; MERCK SHARP & DOHME CORP.; STAMFORD, Andrew, W.; GILBERT, Eric, J.; CUMMING, Jared, N.; WO2012/138590; (2012); A1;,
Pyrimidine | C4H4N2 – PubChem,
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