As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 428854-24-4, name is 2-(1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidine-4,5,6-triamine, molecular formula is C17H15FN8, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below. Recommanded Product: 2-(1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidine-4,5,6-triamine
Acetone (SO ml) was added to 2-(l-(2-fluorobenzyl)-1H-pyrazo]o[3,4-b]pyridin-3-yl) pyrimidine-4,S,6-triamine (10 gms) compound of formula-2 at 25-30C and stirred for 10 minutes at the same temperature. Dimethyl sulfate (10.79 gms) was slowly added to the reaction mixture at 25-30C and stirred for 40 hours at the same temperature. Filtered the precipitated solid, washed with acetone and dried to get the title compound. Yield: 8 gms.
With the rapid development of chemical substances, we look forward to future research findings about 428854-24-4.
Reference:
Patent; MSN LABORATORIES PRIVATE LIMITED, R&D CENTER; THIRUMALAI RAJAN, Srinivasan; ESWARAIAH, Sajja; VENKATA PANAKALA RAO, Gogulapati; RAJESHWAR REDDY, Sagyam; BALA NARSAIAH, Eppaturi; SRINIVASULU, Rangineni; (32 pag.)WO2018/96550; (2018); A1;,
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