Application of 3001-72-7, In the chemical reaction process,reaction time,type of solvent,can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product.An updated downstream synthesis route of 3001-72-7 as follows.
General procedure: A mixture of dimethyl 3-amino-4-cyano-9H-fluorene-1,2-dicarboxylate (1 mmol), carbon disulfide (3 mmol) andDBU or DBN (1 mmol) in DMF (1.5 mL) was stirred for12 h in room temperature. After completion of the reaction(confirmed by TLC), the solvent was removed underreduced pressure. The residue was washed with water (5 ml)and recrystallized from EtOH to afford the pure product.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,3001-72-7, its application will become more common.
Reference:
Article; Ahadi, Somayeh; Zolghadr, Mahdi; Shakibaei, Ghazaleh Imani; Bazgir, Ayoob; Journal of the Iranian Chemical Society; vol. 13; 2; (2016); p. 369 – 375;,
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