Reference of 696-07-1, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 696-07-1, name is 5-Iodouracil. This compound has unique chemical properties. The synthetic route is as follows.
A. Preparation of 5-iodo-2,4-dioxo-3,4-dihydro-2H-pyrimidine-l-carboxylic acid tert-butyl ester; A 500 ml single neck round bottom flask was charged with 5-iodouracil (5.0g, 21mmol) and dry acetonitrile (200ml). Dimethyl amino pyridine (26mg, 0.21mmol) was added in one portion followed by drop wise addition of di-t-butyl di carbonate (5.5g, 25.2mmol) at room temperature and stirred for 3h at room temperature. The reaction mixture was filtered and the organic layer was concentrated under vacuum. Yield = 7.1 (100%)The proton NMR data of the desired product, 5-iodo-2,4-dioxo-3,4-dihydro-2H- pyrimidine-1 -carboxylic acid tert-butyl ester, is provided below: 1H NMR (400 MHz, DMSO-d6, deltappm):CH3)
According to the analysis of related databases, 696-07-1, the application of this compound in the production field has become more and more popular.
Reference:
Patent; JUBILANT BIOSYS LIMITED; WO2007/122634; (2007); A2;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia