Adding a certain compound to certain chemical reactions, such as: 1780-31-0, 2,4-Dichloro-5-methylpyrimidine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Application In Synthesis of 2,4-Dichloro-5-methylpyrimidine, blongs to pyrimidines compound. Application In Synthesis of 2,4-Dichloro-5-methylpyrimidine
A solution of concentrated NH4OH (4.4 mL) in water (20 mL) was added to a suspension of compound XIII-A-59 (2 g) and Zn (2.4 g) in benzene (8 mL). The mixture was heated to reflux overnight. After cooling to room temperature, the solution was filtered and extracted twice with ether. The combined ether solution was dried and concentrated to give 1.0 g of crude product that was more than 90percent pure thus used directly in the next step.
At the same time, in my other blogs, there are other synthetic methods of this type of compound,1780-31-0, 2,4-Dichloro-5-methylpyrimidine, and friends who are interested can also refer to it.
Reference:
Patent; Kalypsys, Inc.; US2005/234046; (2005); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia