Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 1193-21-1, name is 4,6-Dichloropyrimidine. This compound has unique chemical properties. The synthetic route is as follows. Safety of 4,6-Dichloropyrimidine
4,6-Dichloropyrimidine (190 mg, 1.28 mmol, 1.0 equiv.),157 mg p-anisidine (1.27 mmol, 1.0 equiv.), and 180 mg N,N-diisopropylethylamine (1.39 mmol, 1.1 equiv.) were introduced into a Falcon tube, dissolved in NMP, and filled up to a volume of 12.7 cm3 with NMP. The solution was reacted according to general procedure A at 160 Cusing a 4 cm3 coil at a flow rate of 0.5 cm3/min. Crude product was purified as described for the batch synthesis giving pyrimidine 1 as a white, fluffy solid in 81 % yield (243 mg, 1.03 mmol).
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Reference:
Article; Schoen, Michael; Dreier, Dominik; Schnuerch, Michael; Mihovilovic, Marko D.; Monatshefte fur Chemie; vol. 147; 3; (2016); p. 523 – 532;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia