In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 90905-33-2, name is 2-Methylpyrimidine-5-carbaldehyde, the common compound, a new synthetic route is introduced below. Application In Synthesis of 2-Methylpyrimidine-5-carbaldehyde
B) 1-(2-methylpyrimidin-5-yl)ethanolTo a stirred solution of 2-methylpyrimidine-5-carbaldehyde (5.00 g, 38.9 mmol) in tetrahydrofuran (85 mL) was slowly added 33 muL of 1.4 M methylmagnesium bromide solution in tetrahydrofuran at 0° C. The mixture was stirred at room temperature for 1 hour and then quenched with water (50 mL) and extracted with EtOAc (3.x.200 mL). The combined organic layers were dried over sodium sulfate and concentrated in vacuo. The residue was purified by silica gel chromatography (0-100percent EtOAc/hexane) to afford a colorless oil.
The synthetic route of 90905-33-2 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Wei, Zhi-Liang; O’Mahony, Donogh John Roger; Duncton, Matthew; Kincaid, John; Kelly, Michael G.; Wang, Zhan; US2008/275037; (2008); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia