Adding a certain compound to certain chemical reactions, such as: 2557-79-1, 6-Methyl-2-(trifluoromethyl)pyrimidin-4(3H)-one, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 2557-79-1, blongs to pyrimidines compound. Product Details of 2557-79-1
EXAMPLE VI O,O-Diethyl O-(6-methyl-2-(trifluoromethyl)-4-pyrimidinyl)phosphate STR9 A mixture of 3.6 g of 6-methyl-2-(trifluoromethyl)-4-pyrimidinol, 5.0 g of finely powdered potassium carbonate, 40 ml of acetonitrile and 3.45 g of O,O-diethyl chlorophosphate was stirred and heated under reflux for one hour. At this time, no more of the starting phosphorus compound could be detected by glc. The salts were removed by filtration and the filtrate concentrated under reduced pressure. The residue was taken up in ether, the ether solution washed twice with 5 percent aqueous sodium hydroxide solution, once with saturated sodium chloride solution and dried over anhydrous sodium sulfate. The ether was removed in a rotary evaporator leaving 4.0 g of the above-indicated product as an amber colored oil having a refractive index of nd25 =1.4327. The IR and NMR spectra were in agreement with the desired structure. Upon analysis, the product was found to have carbon, hydrogen and nitrogen contents of 38.41, 4.57 and 9.11 percent, respectively, as compared with the theoretical contents of 38.22, 4.49 and 8.92 percent, respectively, as calculated for the above-named structure (Compound 6).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,2557-79-1, its application will become more common.
Reference:
Patent; The Dow Chemical Company; US4575499; (1986); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia