Electric Literature of 1780-26-3, Adding some certain compound to certain chemical reactions, such as: 1780-26-3, name is 2-Methyl-4,6-dichloropyrimidine,molecular formula is C5H4Cl2N2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 1780-26-3.
16.2 g (100 mmol) of 4,6-dichloro-2-methylpyrimidine was added to a solution of 21 g (300 mmol) of hydroxylamine hydrochloride in ethanol (100 ml), and then 30.6 g of triethylamine was added, and the mixture was refluxed at 110 C for 1.5 h. Cool to room temperature, concentrate, wash with water, filter,Drying to obtain 14.3 g of N-(6-chloro-2-methylpyrimidin-4-yl)hydroxylamine (Compound 3),The yield was 90% and the HPLC purity was 99.61%.
According to the analysis of related databases, 1780-26-3, the application of this compound in the production field has become more and more popular.
Reference:
Patent; ANQING QICHUANG PHARMACEUTICAL CO LTD; Anqing Qichuang Pharmaceutical Co., Ltd.; WU XUEPING; Wu Xueping; SHI ZHUYONG; Shi Zhuyong; (10 pag.)CN108299417; (2018); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia