Computed Properties of C6H6BrClN2On March 31, 1984, Sakamoto, Takao; Kondo, Yoshinori; Yamanaka, Hiroshi published an article in Synthesis. The article was 《Studies on pyrimidine derivatives; XXXV. Iodination of 2-aminopyrimidines, 4-aminopyrimidines, and 4-pyrimidinones with iodine chloride in situ》. The article mentions the following:
Iodination of pyrimidines I (R = H, Me, Me2CH, Ph; R1 = NH2; R2 = H; R3 = Me) with ICl generated in situ in AcOH gave 42-55% I (R, R1, R3 = same as above; R2 = I). Similarly, II (R, R2, R3 same as above) gave 51-72% II (R2 = I), which was chlorinated with POCl3 to give I (R, R3 = same, R1 = Cl, R2 = I), which was dechlorinated with p-MeC6H4SO2NHNH2 and Na2CO3 to give 77-87% I (R, R3 = same, R1 = H, R2 = I).5-Bromo-4-chloro-2,6-dimethylpyrimidine(cas: 69696-35-1Computed Properties of C6H6BrClN2) was used in this study.
5-Bromo-4-chloro-2,6-dimethylpyrimidine(cas: 69696-35-1) is a member of organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. They are generally not present in crude oils and are typically the result of additives, cleaning solutions or chemicals used for oil recovery.Computed Properties of C6H6BrClN2
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia