On December 1, 2019, Drozd, Ksenia V.; Manin, Alex N.; Perlovich, German L. published an article.HPLC of Formula: 626-48-2 The title of the article was Comparative analysis of experimental methods for determining thermodynamic parameters of formation of multi-component molecular crystals: Benefits and limitations. And the article contained the following:
In this work, we have studied the processes of dissolution of 4-aminobenzoic acid (PABA) two-component crystals with 6-methyluracil (6-MeUr), pyrazinamide (PyrAm) and emoxypine (EMX) in the pH 7.4 phosphate buffer. The thermodn. functions of cocrystal/salt formation have been estimated from the cocrystal/salt solubility and the corresponding solubility of the pure compounds at various temperatures By analyzing the investigated binary systems, we have compared the accuracy of different exptl. methods in evaluating the thermodn. stability of two PABA cocrystals and one salt: the method of phase solubility diagrams and the cocrystal solubility method. A qual. evaluation of the comparative stability of the cocrystals and salt has been conducted by the competitive reactions method. The lowest value of the Gibbs energy of formation has been found in the PABA cocrystal with 6-MeUr. The fact that the PABA salt with EMX has the highest absolute value of the Gibbs energy of formation is associated with proton transfer. The experimental process involved the reaction of 6-Methylpyrimidine-2,4(1H,3H)-dione(cas: 626-48-2).HPLC of Formula: 626-48-2
The Article related to multi component mol crystal solubility thermodn stability, Phase Equilibriums, Chemical Equilibriums, and Solutions: Phase Equilibriums, Solubility and other aspects.HPLC of Formula: 626-48-2
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia