Kirchmeier, R. L.; Upton, R. P. published an article in 1978, the title of the article was Simultaneous determination of vancomycin, anisomycin, and trimethoprim lactate by high pressure liquid chromatography.Category: pyrimidines And the article contains the following content:
A reverse phase, high pressure liquid chromatog. method for the rapid, accurate, precise, and simultaneous determination of vancomycin [1404-90-6], anisomycin [22862-76-6], and trimethoprim lactate [23256-42-0] was developed, and applied to the determination of these compounds in antibiotic mixtures No chem. methods for the determination of anisomycin have previously been reported. The methods reported in the literature for the determination of vancomycin, and/or trimethoprim lactate are imprecise, nonspecific, or time consuming, and do not allow the simultaneous quant. of anisomycin, vancomycin, and trimethoprim. Precision of the high pressure liquid chromatog. assay was found to be ±1.8%, ±1.1%, and ±2.2% for vancomycin, anisomycin, and trimethoprim lactate, resp. (two standard deviations relative to the average). The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Category: pyrimidines
The Article related to vancomycin anisomycin trimethoprim determination, chromatog anisomycin trimethoprim vancomycin, Pharmaceutical Analysis: Natural Drug Materials and other aspects.Category: pyrimidines
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia