On April 1, 1981, Quintanilla Almagro, Eliseo published a patent.Reference of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate The title of the patent was 2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine 2-hydroxypropionate. And the patent contained the following:
Lactotrim (I) [23256-42-0], the title compound, was prepared by slow addition of 2-hydroxypropanoic acid to an EtOH suspension of 2,4-diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine, during constant agitation. The precipitate was dried under vacuum and controlled temperature The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Reference of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate
The Article related to lactotrim, Pharmaceuticals: Formulation and Compounding and other aspects.Reference of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia