Comparative efficacy and selectivity of some nucleoside analogs against Epstein-Barr virus was written by Lin, Jung Chung; Smith, M. Carolyn; Pagano, Joseph S.. And the article was included in Antimicrobial Agents and Chemotherapy on June 30,1985.Product Details of 69256-17-3 The following contents are mentioned in the article:
The effects of (2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodocytosine (FIAC) [69123-90-6], 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-methyluridine (FMAU) [69256-17-3], 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodouridine (FIAU) [69123-98-4], (E)-5-(2-bromovinyl)-2′-deoxyuridine (BVdU) [69304-47-8], and 9-(1,3-dihydroxy-2-propoxymethyl)guanine (DHPG or BW B759U) [82410-32-0] on the replication of Epstein-Barr virus (EBV) in vitro were evaluated and compared with that of acyclovir (ACV). The relative potencies of these drugs, on the basis of anti-EBV activity, were: FIAC = FIAU > FMAU > DHPG > BVdU > ACV; on the basis of the therapeutic index they were: BVdU > DHPG > FIAC > ACV > FIAU > FMAU. Differential inhibition of EBV-associated polypeptides by these drugs was observed This study involved multiple reactions and reactants, such as 1-((2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione (cas: 69256-17-3Product Details of 69256-17-3).
1-((2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione (cas: 69256-17-3) belongs to pyrimidine derivatives. The pyrimidine nitrogenous bases are derived from the organic compound pyrimidine through the addition of various functional groups. We all know its importance to life – pyrimidine and purine bases are included in the structure of DNA and RNA.Product Details of 69256-17-3
69256-17-3;1-((2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione;The future of 69256-17-3;New trend of C10H13FN2O5;function of 69256-17-3