Sakamoto, Takao published the artcileSelectivity on the homolytic acylation of pyrimidine derivatives, Safety of 1-(6-Methylpyrimidin-4-yl)ethanone, the main research area is homolytic regioselective acylation pyrimidine.
Pyrimidines I [R, R1 = H, Ph; H, Me; RR1 = (CH2)4] were treated with acetyl radical, generated from R2CHO (R2 = Me) FeSO4, tert-BuOOH and H2SO4, to give 25-45% the 4-acetyl derivatives II (R2 = Ac). No 2-acetyl derivatives were formed. Similar reactions using I (R = H, R1 = Ph) and R2CHO (R2 = Et, iso-Pr, Ph) gave 28-50% corresponding II.
Heterocycles published new progress about homolytic regioselective acylation pyrimidine. 67073-96-5 belongs to class pyrimidines, name is 1-(6-Methylpyrimidin-4-yl)ethanone, and the molecular formula is C7H8N2O, Safety of 1-(6-Methylpyrimidin-4-yl)ethanone.
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia