Preparation of pyrimidine isocyanates was written by Dyer, Elizabeth;Nycz, Thomas J.;Long, Michael B.. And the article was included in Journal of Heterocyclic Chemistry in 1972.Application of 39513-47-8 The following contents are mentioned in the article:
Uracil-5-yl isocyanate and 1,3-dimethyluracil-5-yl isocyanate were prepared from the corresponding new carboazides. 1,3-Dimethyluracil-5-ylmethyl isocyanate obtained from the chloro compound and silver cyanate, was polymerized with an anionic initiator to the cyclic trimer. Attempts to isolate uracil-6-yl isocyanate, 1,3-dimethyluracil-6-yl isocyanate, 4-pyrimidinyl isocyanate, and 2,6-dichloro-4-pyrimidinyl isocyanate were unsuccessful. Ethyl carbamate derivatives were made from all new azides and isocyanates. Other new pyrimidine derivatives included N,N’-bis(4-pyrimidinylcarbonyl)hydrazine, N,N’-bis(1,3-dimethyluracil-5-yl)urea, N,N’-bis(1,3-dimethyluracil-6-yl)urea, and N,N’-bis(2,5,-6,-trichloro-4-pyrimidinyl)oxamide. This study involved multiple reactions and reactants, such as Ethyl 1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (cas: 39513-47-8Application of 39513-47-8).
Ethyl 1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (cas: 39513-47-8) belongs to pyrimidine derivatives. The aromatic compound pyrimidine, and its derivatives, are ubiquitous in nature. They are found in nucleic acids, vitamins, amino acids, antibiotics, alkaloids, and a variety of toxins. Drugs having the pyrimidine motif have manifested to exhibit gratifying biological activity like anticancer, antiviral, anti-inflammatory, antibacterial, and antihypertensive activities.Application of 39513-47-8
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia