Convenient synthesis of pyrido[4,3-d]pyrimidine-2,4(1H,3H)-diones was written by Hirota, Kosaku;Nakazawa, yukio;Kitade, Yukio;Sajiki, Hironao. And the article was included in Heterocycles in 1998.Quality Control of Ethyl 1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate The following contents are mentioned in the article:
Title compounds such as I (R = H, NH2, OH) were prepared from uracils such as II (R1 = CHO, CN, COOEt). This study involved multiple reactions and reactants, such as Ethyl 1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (cas: 39513-47-8Quality Control of Ethyl 1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate).
Ethyl 1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (cas: 39513-47-8) belongs to pyrimidine derivatives. The pyrimidine nitrogenous bases are derived from the organic compound pyrimidine through the addition of various functional groups. For example, the neurotoxin tetrodotoxin is a pyrimidine derivative. It is found in a number of species including the Japanese puffer fish, the blue-ringed octopus, and the orange-bellied newt. Tetrodotoxin prevents the transmission of nerve signals and can result in paralysis and death.Quality Control of Ethyl 1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia