Shakhmin, Anton et al. published their research in Chemistry – A European Journal in 2016 | CAS: 90905-32-1

2-Methoxypyrimidine-5-carbaldehyde (cas: 90905-32-1) belongs to pyrimidine derivatives. The pyrimidine derivatives can easily interact with enzymes, genetic materials, and bio components within the cell. For example, the neurotoxin tetrodotoxin is a pyrimidine derivative. It is found in a number of species including the Japanese puffer fish, the blue-ringed octopus, and the orange-bellied newt. Tetrodotoxin prevents the transmission of nerve signals and can result in paralysis and death.Reference of 90905-32-1

Three Efficient Methods for Preparation of Coelenterazine Analogues was written by Shakhmin, Anton;Hall, Mary P.;Walker, Joel R.;Machleidt, Thomas;Binkowski, Brock F.;Wood, Keith V.;Kirkland, Thomas A.. And the article was included in Chemistry – A European Journal in 2016.Reference of 90905-32-1 This article mentions the following:

The growing popularity of bioluminescent assays has highlighted the need for coelenterazine analogs possessing properties tuned for specific applications. However, the structural diversity of known coelenterazine analogs has been limited by current syntheses. Known routes for the preparation of coelenterazine analogs employ harsh reaction conditions that limit access to many substituents and functional groups. Novel synthetic routes reported here establish simple and robust methods for synthesis and investigation of structurally diverse marine luciferase substrates. Specifically, these new routes allow synthesis of coelenterazine analogs containing various heterocyclic motifs and substituted aromatic groups with diverse electronic substituents at the R2 position. Interesting analogs described herein were characterized by their physicochem. properties, bioluminescent half-life, light output, polarity and cytotoxicity. Some of the analogs represent leads that can be utilized in the development of improved bioluminescent systems. In the experiment, the researchers used many compounds, for example, 2-Methoxypyrimidine-5-carbaldehyde (cas: 90905-32-1Reference of 90905-32-1).

2-Methoxypyrimidine-5-carbaldehyde (cas: 90905-32-1) belongs to pyrimidine derivatives. The pyrimidine derivatives can easily interact with enzymes, genetic materials, and bio components within the cell. For example, the neurotoxin tetrodotoxin is a pyrimidine derivative. It is found in a number of species including the Japanese puffer fish, the blue-ringed octopus, and the orange-bellied newt. Tetrodotoxin prevents the transmission of nerve signals and can result in paralysis and death.Reference of 90905-32-1

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia