Synthesis of N-tetra-O-acetyl-β-D-glucopyranosyl-N’-(4′,6′-diarylpyrimidin-2′-yl)thioureas was written by Nguyen, Dinh Thanh;Nguyen, Thi Thanh Mai. And the article was included in Carbohydrate Research in 2009.Application of 40230-24-8 This article mentions the following:
Some 2-amino-4,6-diarylpyrimidines, e.g. I, have been prepared from substituted benzylideneacetophenones and guanidine hydrochloride in the presence of alkali by conventional heating in alc. medium and microwave heating in solvent-free conditions. N-(2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl)-N’-(4′,6′-diarylpyrimidin-2′-yl)thioureas 4 have been synthesized by reaction of per-O-acetylated glucopyranosyl isothiocyanate and substituted 2-amino-4,6-diarylpyrimidines. Two different methods have been used, namely, refluxing in anhydrous dioxane and solvent-free microwave-assisted coupling. The second procedure afforded higher yields in much shorter reaction times. The compounds I and II were tested for their antibacterial and antifungal activities in vitro against Staphylococcus epidermidis, Enterobacter aerogenes and Candida albicans by disk diffusion method. In the experiment, the researchers used many compounds, for example, 4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8Application of 40230-24-8).
4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8) belongs to pyrimidine derivatives. The pyrimidine derivatives can easily interact with enzymes, genetic materials, and bio components within the cell. We all know its importance to life – pyrimidine and purine bases are included in the structure of DNA and RNA.Application of 40230-24-8
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia