Mass spectra of pyrimidine derivatives. V. Methoxy- and dimethylaminopyrimidines was written by Ivanovskaya, L. Yu.;Derendyaev, B. G.;Baram, S. G.. And the article was included in Izvestiya Sibirskogo Otdeleniya Akademii Nauk SSSR, Seriya Khimicheskikh Nauk in 1982.Safety of 4-Chloro-2-methoxypyrimidine This article mentions the following:
The mass spectra of I (R = H, F, Cl), II (R = H, F; R1 = H, F, Cl), III, IV (R = F, Cl), V, and VI (R = H, Cl; R1 = H, Me, MeO, F, Cl, NO2) were analyzed. In the case of VI (R = H), electron-donating R1 substituents favored cleavage of a C-H bond in the OMe group, whereas electron-withdrawing R1 favored loss of CH2O. In the experiment, the researchers used many compounds, for example, 4-Chloro-2-methoxypyrimidine (cas: 51421-99-9Safety of 4-Chloro-2-methoxypyrimidine).
4-Chloro-2-methoxypyrimidine (cas: 51421-99-9) belongs to pyrimidine derivatives. Pyrimidines are isomeric with two other forms of diazines: pyridazine, with the nitrogen atoms in the 1 and 2 positions; and pyrazine, with the nitrogen atoms in the 1 and 4 positions. For example, the neurotoxin tetrodotoxin is a pyrimidine derivative. It is found in a number of species including the Japanese puffer fish, the blue-ringed octopus, and the orange-bellied newt. Tetrodotoxin prevents the transmission of nerve signals and can result in paralysis and death.Safety of 4-Chloro-2-methoxypyrimidine
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia