Reaction of α,β-unsaturated ketones with guanidine. Substituent effects on the protonation constants of 2-amino-4,6-diarylpyrimidines was written by Al-Hajjar, Farouk H.;Sabri, Salim S.. And the article was included in Journal of Heterocyclic Chemistry in 1982.Recommanded Product: 4,6-Diphenylpyrimidin-2-amine This article mentions the following:
RCH:CHCOR1 (R = e.g., Ph, p-MeC6H4, m-O2NC6H4, p-FC6H4; R1 = Ph, p-MeC6H4) is condensed with NH:C(NH2)2·HCl, in aqueous EtOH containing NaOH, to give the corresponding I. LFER for the protonation constants of I (R1 = Ph, p-MeC6H4), in 50 volume% aqueous EtOH, vs. σ, σ*XC6H4, and a dual parameter Hammett equation in σR and σI were obtained. In the experiment, the researchers used many compounds, for example, 4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8Recommanded Product: 4,6-Diphenylpyrimidin-2-amine).
4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8) belongs to pyrimidine derivatives. The pyrimidine derivatives can easily interact with enzymes, genetic materials, and bio components within the cell. We all know its importance to life – pyrimidine and purine bases are included in the structure of DNA and RNA.Recommanded Product: 4,6-Diphenylpyrimidin-2-amine
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia