Reaction of 1,3-diaryl-2,3-dibromo-1-propanones with urea in basic and acidic medium. Synthesis of pyrimidine, imidazoline and imidazolidine derivatives was written by Dora, E. Khalli;Dash, Bhabagrahi;Panda, C. S.. And the article was included in Journal of Heterocyclic Chemistry in 1983.HPLC of Formula: 40230-24-8 This article mentions the following:
RCOCHBrCHBrR1 [I, R, R1 = (un)substituted phenyl] underwent cyclization with H2NCONH2 in basic medium to give the pyrimidines II (R2 = Br, R3 = H, X = O), which were converted to II (R2R3 = X = O, S). I reacted with R4NHCONH2 (R4 = H, Ph) and PhNHCONHPh in AcOH to give the imidazoles III and IV, resp. In the experiment, the researchers used many compounds, for example, 4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8HPLC of Formula: 40230-24-8).
4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8) belongs to pyrimidine derivatives. The aromatic compound pyrimidine, and its derivatives, are ubiquitous in nature. They are found in nucleic acids, vitamins, amino acids, antibiotics, alkaloids, and a variety of toxins. We all know its importance to life – pyrimidine and purine bases are included in the structure of DNA and RNA.HPLC of Formula: 40230-24-8
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia