Morpholino pyrimidinyl acetamides: design, green chemical one-pot synthesis, and in vitro microbiological evaluation was written by Kanagarajan, V.;Gopalakrishnan, M.. And the article was included in Pharmaceutical Chemistry Journal in 2011.SDS of cas: 40230-24-8 This article mentions the following:
Morpholinylpyrimidinylacetamides I (R = H, Me, F; R1 = H, OMe, F) were synthesized by green “one-pot” reaction under microwave irradiation in dry medium. The synthesized compounds were characterized by m.p., elemental anal., mass spectrometry, FT-IR spectroscopy, and one-dimensional NMR (1H and 13C) spectroscopic data. All the synthesized compounds were screened for their in vitro antibacterial and antifungal activities against clin. isolated bacterial strains of Bacillus subtilis, Bacillus cerues, Micrococcus luteus, Salmonella typhii, Shigella felxneri and fungal strains of Aspergillus niger, Candida albicans, Candida 6 and Candida 51 and the results are discussed. In the experiment, the researchers used many compounds, for example, 4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8SDS of cas: 40230-24-8).
4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8) belongs to pyrimidine derivatives. Pyrimidine also found in many synthetic compounds such as barbiturates and the HIV drug, zidovudine. For example, the neurotoxin tetrodotoxin is a pyrimidine derivative. It is found in a number of species including the Japanese puffer fish, the blue-ringed octopus, and the orange-bellied newt. Tetrodotoxin prevents the transmission of nerve signals and can result in paralysis and death.SDS of cas: 40230-24-8
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia