Reaction of N-(carbamimidoyl)thiourea with 1-benzoyl-2-phenylacetylene was written by Glotova, T. E.;Dvorko, M. Yu.;Albanov, A. I.;Protsuk, N. I.. And the article was included in Russian Journal of Organic Chemistry in 2007.SDS of cas: 40230-24-8 This article mentions the following:
1-Benzoyl-2-phenylacetylene reacted with N-(carbamimidoyl)thiourea H2NC(:S)NHC(:NH)NH2 in glacial acetic acid saturated with 20% HBr to give (4,6-diphenyl-2H-1,3-thiazin-2-ylidene)guanidine hydrobromide. The reaction of the same compounds in anhydrous EtOH in the presence of NaOEt led to the formation of N-(4,6-diphenylpyrimidin-2-yl)thiourea. Bis(3-oxo-1,3-diphenylprop-1-en-1-yl) sulfide and 1-benzoyl-2-ethylsulfanyl-2-phenylethylene were isolated in the reactions of 1-benzoyl-2-phenylacetylene with N-(carbamimidoyl)thiourea and N-(carbamimidoyl)-S-ethylisothiuronium bromide, resp., in anhydrous MeOH. In the experiment, the researchers used many compounds, for example, 4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8SDS of cas: 40230-24-8).
4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8) belongs to pyrimidine derivatives. Pyrimidines are isomeric with two other forms of diazines: pyridazine, with the nitrogen atoms in the 1 and 2 positions; and pyrazine, with the nitrogen atoms in the 1 and 4 positions. Drugs having the pyrimidine motif have manifested to exhibit gratifying biological activity like anticancer, antiviral, anti-inflammatory, antibacterial, and antihypertensive activities.SDS of cas: 40230-24-8
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia