Application of 6320-15-6, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 6320-15-6, name is 4-Chloro-2,6-dimethoxypyrimidine. A new synthetic method of this compound is introduced below.
Prepared in a similar manner to Example 7 using 6-chloro-2,4-dimethoxypyrimidine to give the title compound (19 mg, 14%). 1H NMR (400 MHz, CDCl3) ? 8.68 (1H, d, J=1.2 Hz), 8.12 (1H, dd, J=8.1, 1.7 Hz), 7.56-7.36 (6H, m), 6.84 (1H, s), 4.11 (3H, s), 4.06 (2H, s), 4.04 (3H, s), 2.73 (3H, s), m/z (ES+) 453 (M+H)+.
At the same time, in my other blogs, there are other synthetic methods of this type of compound,6320-15-6, 4-Chloro-2,6-dimethoxypyrimidine, and friends who are interested can also refer to it.
Reference:
Patent; Boase, Amanda Louise; Ladduwahetty, Tamara; MacLeod, Angus Murray; Merchant, Kevin John; US2004/58970; (2004); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia