The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 6630-30-4, name is 6-Chloro-5-nitropyrimidine-2,4-diol. This compound has unique chemical properties. The synthetic route is as follows. Recommanded Product: 6-Chloro-5-nitropyrimidine-2,4-diol
6-Chloro-5-nitro-1H-pyrimidine-2,4-dione (25.6 g, 134 mmol) is mixed with THF (300 mL) and cooled to 0 C. Sodium thiomethylate (25.0 g, 357 mmol) is added in portions (temperature<5 C.). The reaction mixture is stirred for 16 h, poured into hydrochloric acid (1 M in H2O; 1000 mL) at 0 C. and stirred for 1 h. The precipitate is filtered off, washed with ice-water and EA and dried to yield the product that is taken to the next step without further purification. [0420] Rf (EA/MeOH 8:2)=0.28
With the rapid development of chemical substances, we look forward to future research findings about 6630-30-4.
Reference:
Patent; Boehringer Ingelheim International GmbH; GERLACH, Kai; EICKMEIER, Christian; HEINE, Claudia; HEINE, Niklas; WEBER, Alexander; US2013/225549; (2013); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia