In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 32779-36-5, name is 5-Bromo-2-chloropyrimidine, the common compound, a new synthetic route is introduced below. Recommanded Product: 5-Bromo-2-chloropyrimidine
5-bromo-2-chloropyrimidine (1g, 5.17mmol) was dissolved in N, N- dimethylformamide (20 mL) was added 4-hydroxypiperidine (522.7mg, 5.17mmol) and triethylamine (1.05 g, 10.34mmol), The reaction was heated to 100C 16 hours, the reaction was complete TLC (PE: EA = 5: 1), water (20 mL), extracted with ethyl acetate (50mL ¡Á 2), the organic phases were combined, washed with water, without over anhydrous sodium sulfate, and concentrated in vacuo to give the title compound (1.3 g of, yield 97.7percent)
The synthetic route of 32779-36-5 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Shandong xuanzhu Pharmaceutical Technology Co., Ltd.; Wu, Yongqian; Tian, Yuwei; (59 pag.)CN106167486; (2016); A;,
Pyrimidine | C4H4N2 – PubChem,
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