Related Products of 938443-20-0, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.938443-20-0, name is 2,4,7-Trichloropyrido[2,3-d]pyrimidine, molecular formula is C7H2Cl3N3, molecular weight is 234.4699, as common compound, the synthetic route is as follows.
The 2,4,7-trichloro-pyrido [2,3-d] pyrimidine (1g, 4.29mmol), and 8-oxa-3-azabicyclo [3.2.1] nonane hydrochloride (640mg, 4.29 mmol) were dissolved 20mLDCM added dropwise DIEA (0.9mL, 5.15mmol) under ice-cooling.After the reaction was stirred at room temperature for 18H, reaction mixture was washed, the organic layer was dried and concentrated to give a solid, which was used without purification was used directly in the next reaction.
The chemical industry reduces the impact on the environment during synthesis 938443-20-0, I believe this compound will play a more active role in future production and life.
Reference:
Patent; Shandong Xuanzhu Pharmaceutical Technology co., LTD; WU, YONG QIAN; WANG, AI CHEN; (35 pag.)CN102887895; (2016); B;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia