Application of 49844-90-8, Adding some certain compound to certain chemical reactions, such as: 49844-90-8, name is 4-Chloro-2-(methylthio)pyrimidine,molecular formula is C5H5ClN2S, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 49844-90-8.
4-Chloro-2-methylthiopyrimidine (9 g, 56.0 mmol) was added to 47% HI (55 mL) solution and the mixture was stirred at room temperature for 48 hours. The precipitated solids were filtered, dissolved in water (100 mL) and added 20% NaOH to adjust pH 8. The mixture was extracted with chloroform and the extract was washed with water and dried over MgSO4 and, subsequently, the solvent was evaporated. The residue was recrystallized from petroleum ether to give the title compound (9.5 g, 36.7 mmol, yield 67%).1H-NMR (CDCl3) delta: 2.54 (s, 3H), 7.41 (d, IH), 8.01 (d, IH)
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 49844-90-8, 4-Chloro-2-(methylthio)pyrimidine, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; DONGBU HANNONG CHEMICALS CO., LTD.; WO2006/137658; (2006); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia