Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 4595-61-3, name is Pyrimidine-5-carboxylic acid. A new synthetic method of this compound is introduced below., Formula: C5H4N2O2
Example 2 1,4,5,6-Tetrahydropyrimidine-5-carboxylic Acid Hydrochloride Pyrimidine-5-carboxylic acid (5.0 g, 40 mmol) was suspended in a mixture of 150 ml water and concentrated hydrochloric acid (4.0 g, 40.5 mmol). The mixture was hydrogenated at 26 psig over 1.0 g Pd-on-carbon 10percent in a Parr hydrogenator for 3 h. The suspension was filtered and the filter rinsed twice with hot water (20 ml). The filtrate was evaporated in vacuo to give 6.11 g yellow oil (92percent). The oil was crystallized from anhydrous methanol/tetrahydrofuran (THF) to give 5.77 g (87percent) white crystals in two crops. 300 MHz nmr indicated product.
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Reference:
Patent; The University of Toledo; US5175166; (1992); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia