Related Products of 39889-94-6, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 39889-94-6, name is 5-Amino-2-methylpyrimidine, molecular formula is C5H7N3, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
The mixture of mono-sufone (50.6 mg, 0.1 mmol), 2-methylpyrimidin-5-amine (109 mg, 1.0 mmol), and K2CO3 (138.1 mg, 1.0 mmol) in NMP (0.5 mL) was heated to 140 C for 17 hrs, cooled to room temperature, and TFA (15 mL) was added and stirred for 5 minutes. After removal of the solvent, prep-HPLC of the residue gave the desired product. MS (ESI) m/z 435 (M + H)+.
According to the analysis of related databases, 39889-94-6, the application of this compound in the production field has become more and more popular.
Reference:
Patent; TRIUS THERAPEUTICS, INC.; FINN, John; TARI, Leslie, William; CHEN, Zhiyong; ZHANG, Junhu; PHILLIPSON, Douglas; LEE, Suk, Joong; TRZOSS, Michael; BENSEN, Daniel; LI, Xiaoming; TENG, Min; ONG, Voon; BORCHARDT, Allen, John; LAM, Thanh, To; WO2015/38661; (2015); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia