Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 36315-01-2, Name is 2-Amino-4,6-dimethoxypyrimidine, molecular formula is C6H9N3O2, belongs to pyrimidines compound, is a common compound. In a patnet, author is Pandya, M. K., once mentioned the new application about 36315-01-2, Recommanded Product: 2-Amino-4,6-dimethoxypyrimidine.
Synthesis of Lanso Aminopyrimidines as Dominant Chemotherapeutic Agents for Leukaemia
In the present paper we synthesized 10 unique pyrimidine scaffolds (Lanso Aminopyrimidines) derived from 4-(2,2,2-trifluoroethoxy)-2-(chloromethyl)-3-methylpyridine as a core molecule, which can be used for the design of more potent and effective anticancer agents. The in vitro anticancer activities of the synthesized new pyrimidine derivatives were screened at the National Cancer Institute, USA, against a full NCI 60 cell lines. Most of the compounds exhibited remarkable growth inhibition at a single dose (10 mu M) in Leukaemia cancer cell. 4-(4-{3-Methyl-4-[(2,2,2-trifluoroethoxy)pyridin-2-yl]methylamino}phenyl)-6-phenyl-1,6-dihydropyrimidin-2-amine which showed high activity against RPMI-8226 leukaemia cancer cells (GI(50) 35.50 mu M) and can be considered as a candidate lead compound for developing new promising anticancer agents.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 36315-01-2. The above is the message from the blog manager. Recommanded Product: 2-Amino-4,6-dimethoxypyrimidine.
Reference:
Pyrimidine | C4H4N2 – PubChem,
,Pyrimidine – Wikipedia