The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 5751-20-2, name is 2-(Methylthio)pyrimidin-4(3H)-one. This compound has unique chemical properties. The synthetic route is as follows. Computed Properties of C5H6N2OS
EXAMPLE 4; N4-(3-(dimethylamino)propyl)-N2-m-biphenylpyrimidine-2,4-diamine hydrochloride (11); Preparation of 2-(3-biphenylamino)pyrimidin-4(3H)-one (9): To 2-(methylthio)-pyrimidine-4(3H)-one, 1, (790 mg, 5.5 mmol) in diglyme (5 mL) is added 3-amino-biphenyl (1.91 g, 11.2 mmol). The resulting mixture is stirred at reflux for 18 hours. The mixture is cooled to room temperature and hexane is added and a precipitate forms which is collected by filtration to afford 1.34 g (92percent yield) of the desired compound which is used without further purification. MS (ESI, pos. ion) m/z: 264 (M+1).
With the rapid development of chemical substances, we look forward to future research findings about 5751-20-2.
Reference:
Patent; DJUNG, Jane Far-Jine; Golebiowski, Adam; Hunter, Jack A.; Shrum, Gary P.; US2007/293525; (2007); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia