Related Products of 873-83-6, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 873-83-6, name is 6-Aminopyrimidine-2,4(1H,3H)-dione, molecular formula is C4H5N3O2, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
196 g of water and 4 g of PTS were added to a 500 ml glass reactor equipped with mechanical stirring, stirred at 70 C for 2 hours, cooled to 55 C, and solid 6-aminouracil (20.0 g, 1.0 eq., 157.4 mmol) was added and stirred to form a suspension. Then, benzaldehyde (10.0 g, 0.6 eq., 94.4 mmol) was added and stirred at 55 C for 5-8 hours at high speed to obtain an off-white suspension. The progress of the reaction was confirmed by HPLC or TLC to ensure complete conversion of the starting material, cooling to 30 C, filtration The filter cake was washed with 30 ml of hot water, and the wet cake was air-dried at 100 C for 3 hours to obtain 24.0 g of a white solid with a purity of 97.9% and a yield of 89.1%.
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 873-83-6, 6-Aminopyrimidine-2,4(1H,3H)-dione.
Reference:
Patent; Guangzhou Zhenlaimai New Materials Technology Co., Ltd.; Xiao Juan; Qi Tafamingrenqingqiubugongkaixingming; (11 pag.)CN110041270; (2019); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia