The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 302964-08-5, name is 2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide. This compound has unique chemical properties. The synthetic route is as follows. Safety of 2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide
2-oxa-6-thiospiro [3.3] heptan-6-oxalate oxalate (55,359 mg, 1.02 mmol) was added to a solution of 2- ((6-chloro-2-methyl Yl) amino) -n- (2-chloro-6-methylphenyl) thiazole-5-carboxamide (52,200 mg, 0.51 mmol) and N, N-diisopropylethylamine (0 (35 mL), 2.04 mmol) in 1,4-dioxane (5 mL), heated to reflux, reacted overnight, and TLC monitored the disappearance of the starting material. The reaction was stopped at room temperature and the solvent was removed. The resulting solid was washed twice with methanol and diethyl ether and separated by high performance liquid chromatography to give a pale yellow solid (10 mg, yield 4%). 1
With the rapid development of chemical substances, we look forward to future research findings about 302964-08-5.
Reference:
Patent; Fudan University; Dong, Xiaochun; Zhao, WeiLi; Zhao, Yichao; Lin, Zhaohu; Lu, Xiuhong; Wang, Wen; Dong, Qian; (12 pag.)CN104151321; (2016); B;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia