Related Products of 13509-52-9, Adding some certain compound to certain chemical reactions, such as: 13509-52-9, name is 1,3,6-Trimethylpyrimidine-2,4(1H,3H)-dione,molecular formula is C7H10N2O2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 13509-52-9.
Step 2: 6-[(£)-2-(Dimethylamino)vinyl]- l,3-dimethylpyrimidine-2,4(lH,3H)-dione: A mixture of Step 1 intermediate (40.0 g, 259.70 mmol) and N,N-dimethyl formamide dimethyl acetal (206 ml, 1549.12 mmol) in dry DMF (80 ml) was heated at 90C for 48 h. The reaction mixture was cooled to room temperature and diluted with diethyl ether (100 ml). The precipitated solid was filtered, washed with diethyl ether (2 x 50 ml) and dried to obtain 34 g of product as off-white solid. -NMR (300 MHz, CDCI3) delta 2.95 (s, 6H), 3.33 (s, 3H), 3.43 (s, 3H), 4.62 (d, J = 12.6 Hz, 1 H), 5.58 (s, 1 H), 7.03 (d, J = 12.6 Hz, l H).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 13509-52-9, 1,3,6-Trimethylpyrimidine-2,4(1H,3H)-dione, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; GLENMARK PHARMACEUTICALS S.A.; KUMAR, Sukkeerthi; THOMAS, Abraham; WAGHMARE, Nayan, Taterao; KHAIRATKAR-JOSHI, Neelima; MUKHOPADHYAY, Indranil; WO2011/132017; (2011); A1;,
Pyrimidine | C4H4N2 – PubChem,
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