Adding a certain compound to certain chemical reactions, such as: 56-09-7, 2-Amino-6-hydroxypyrimidin-4(3H)-one, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 56-09-7, blongs to pyrimidines compound. SDS of cas: 56-09-7
a 2-Amino-4,6-dichloro-pyrimidine-5-carbaldehyde Following the method of Bell et al. (J. Heterocyclic Chem. 1983, 20, 41), to 97.0 ml (1.06 mol) phosphorus oxychloride in a 2-necked flask cooled to 5 C. was added dropwise with stirring 32.5 ml (0.42 mol) DMF. The mixture was allowed to warm to room temperature and then 25.0 g (0.20 mol) 2-amino-4,6-dihydroxy-pyrimidine was added in small portions over 30 minutes. The reaction mixture was then heated at 100 C. for 4.5 hours before being poured cautiously onto water cooled to 10 C. and left standing at room temperature overnight. The resulting crystals were collected by filtration, and extracted with 4*450 ml hot ethyl acetate.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,56-09-7, its application will become more common.
Reference:
Patent; Borroni, Edilio Maurizio; Huber-Trottmann, Gerda; Kilpatrick, Gavin John; Norcross, Roger David; US2001/27196; (2001); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia