Synthetic Route of 2565-47-1, Adding some certain compound to certain chemical reactions, such as: 2565-47-1, name is 1-Methylpyrimidine-2,4,6(1H,3H,5H)-trione,molecular formula is C5H6N2O3, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 2565-47-1.
(b) 6-Chloro-3-methylpyrimidine-2,4(l/J,3H)-dioneWater (2.7 mL) is added dropwise to a suspension of 1-methylpyrimidine- 2,4,6(lH,3H,5No.)-trione (14.2 g, 100 mol) in POCl3 (95 mL) at 0 0C. The reaction mixture is then heated at 80 C for 5 hours. The resulting brownish solution is cooled, and POCl3 is evaporated under reduced pressure. The residue is treated with MeOH, and the obtained solid is recrystallized from ethanol to give 11.5 g product (Yield: 71.6%). m.p. = 279-282 0C (dec) [Lit.2: 280-282 0C]. 1H NMR (400 MHz, DMSO-d6) (53.10 (S, 3H), 5.90 (S, IH), 12.4 (br, IH).
According to the analysis of related databases, 2565-47-1, the application of this compound in the production field has become more and more popular.
Reference:
Patent; INTRA-CELLULAR THERAPIES, INC.; WO2006/133261; (2006); A2;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia