Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 54535-00-1, name is (5,7-Dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methanol. A new synthetic method of this compound is introduced below., Recommanded Product: (5,7-Dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methanol
Under ice bath, intermediate b3 (2.0 g, 11.0mmol) was solubilized in dichloromethane (10 mL). a solution ofthionyl chloride (12.0 mmol) in dichloromethane (10 mL) wasadded drop-wise. The mixture was stirred at rt for 3 h. After that,the solvent was removed under reduced pressure and ethyl acetatewas added, then the mixture was washed by saturated sodiumbicarbonate solution followed by brine, and dried with Na2SO4, filteredand evaporated in vacuo to get yellow solid (1.9 g, 89%). MS[M+H]+ m/z: 197.
If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 54535-00-1, (5,7-Dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methanol.
Reference:
Article; Liu, Moyi; Xu, Qiaoling; Guo, Su; Zuo, Ruixi; Hong, Yue; Luo, Yong; Li, Yingxiu; Gong, Ping; Liu, Yajing; Bioorganic and Medicinal Chemistry; vol. 26; 9; (2018); p. 2621 – 2631;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia