A new synthetic route of 89487-99-0

Statistics shows that 89487-99-0 is playing an increasingly important role. we look forward to future research findings about 4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile.

Synthetic Route of 89487-99-0, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.89487-99-0, name is 4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile, molecular formula is C6H5N3OS, molecular weight is 167.19, as common compound, the synthetic route is as follows.

4-Hydroxy-2-(methylthio) pyrimidine-5-carbonitrile (3 mmol) and m-anisidine (3 mmol) in pentan-1-ol was refluxed for 40 h under nitrogen. The reaction mixture was concentrated in vacuo. The residue was washed with water and dried to afford 4-hydroxy-2-(3-methoxyphenylamino)pyrimidine-5-carbonitrile.

Statistics shows that 89487-99-0 is playing an increasingly important role. we look forward to future research findings about 4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile.

Reference:
Patent; Hutchison MediPharma Enterprises Limeted; US2008/255172; (2008); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia