Adding a certain compound to certain chemical reactions, such as: 22536-67-0, 2,5-Dichloropyrimidine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Recommanded Product: 2,5-Dichloropyrimidine, blongs to pyrimidines compound. Recommanded Product: 2,5-Dichloropyrimidine
Step A: 5 -chloro-2-(methylsulfanyl)pyrimidine: A stirred solution of 2,5 -dichloropyrimidine(2.0 g, 13 mmol) in DMF (10 mL) was treated with sodium thiomethoxide (1.0 g, 15 mmol).After 2h, the solution was diluted with brine and extracted with EtOAc. The organic layer wasremoved, dried over Mg504, filtered and concentrated giving rise to an oil. The oil was usedcrude in next step.
The synthetic route of 22536-67-0 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; MERCK SHARP & DOHME CORP; TANG, Haifeng; PIO, Barbara; JIANG, Jinlong; PASTERNAK, Alexander; DONG, Shuzhi; FERGUSON, Ronald Dale, II; GUO, Zack Zhiqiang; CHOBANIAN, Harry; FRIE, Jessica; GUO, Yan; WU, Zhicai; YU, Yang; WANG, Ming; WO2015/17305; (2015); A1;,
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