Related Products of 16234-10-9, Adding some certain compound to certain chemical reactions, such as: 16234-10-9, name is Thieno[3,2-d]pyrimidin-4(3H)-one,molecular formula is C6H4N2OS, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 16234-10-9.
Thieno[3,2-d]pyrimidin-4(3H)-one (38.0 g, 0.25 mol) was dissolved in acetic acid (143 mL, 2.5 mol), and bromine (40.4 mL, 0.78 mol) diluted with acetic acid (122 mL, 2.1 mol) was slowly added to the solution prepared. The reaction solution was stirred in a sealed reactor for 18 hours at 120C. The reaction solution was cooled to room temperature and acetic acid was removed by distillation under reduced pressure. The reaction mixture was poured into an ice water to generate a solid compound, and the resulting solid compound was filtered and dried. The title compound was obtained without purification (37.5 g, 65%). 1H-NMR Spectrum (300 MHz, DMSO-d6): delta 12.75 (brs, 1H), 8.36 (s, lh), 8.24 (s, 1H)
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 16234-10-9, Thieno[3,2-d]pyrimidin-4(3H)-one, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; HANMI PHARM CO., LTD.; BAE, In Hwan; SON, Jung Beom; HAN, Sang Mi; KWAK, Eun Joo; KIM, Ho Seok; SONG, Ji Young; BYUN, Eun Young; JUN, Seung Ah; AHN, Young Gil; SUH, Kwee Hyun; WO2013/100632; (2013); A1;,
Pyrimidine | C4H4N2 – PubChem,
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