Introduction of a new synthetic route about (2-Methoxypyrimidin-4-yl)methanamine

With the rapid development of chemical substances, we look forward to future research findings about 944901-04-6.

The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 944901-04-6, name is (2-Methoxypyrimidin-4-yl)methanamine. This compound has unique chemical properties. The synthetic route is as follows. category: pyrimidines

A solution of 2-methoxy-pyrimidin-4-yl-methylamine (200 mg) and DIPEA (928mg) in DCM (10ml) was cooled to about 00C and a solution of 5-cyclopentyloxybenzene- sulfonylchloride (356mg) in DCM (10ml) was slowly added. After stirring for 14h, the crude product was adsorbed to silica and purified by means of column chromatography and the title compound obtained as a white solid (30%). Melting point: 11 10C.

With the rapid development of chemical substances, we look forward to future research findings about 944901-04-6.

Reference:
Patent; BASF SE; WO2009/141291; (2009); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia