The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 3438-48-0, name is 4-Phenylpyrimidine. This compound has unique chemical properties. The synthetic route is as follows. Recommanded Product: 3438-48-0
General procedure: A stirred mixture of pyrimidine 1 (2.5 mmole), 2-bromoacetophenone 2 (2.5 mmole) and non-symmetrical electron deficient alkynes 3 (3.5 mmole) in 15 mL 1,2-epoxybutane was placed into an sealed microwave reactor at120 C for 30 min. The reaction mixture was cooled to room temperature, partly of the solvent was removed in vacuum, 5mL of MeOH was added under a gentle stirring and themixture was left overnight at 5-10 C . The solid formed was filtered-off, washed on the filter with a mixture of diethylether-MeOH 2:1 and crystallized from CHCl3/MeOH.
With the rapid development of chemical substances, we look forward to future research findings about 3438-48-0.
Reference:
Article; Georgescu, Emilian; Georgescu, Florentina; Draghici, Constantin; Cristian, Liliana; Popa, Marcel Mirel; Dumitrascu, Florea; Combinatorial Chemistry and High Throughput Screening; vol. 16; 10; (2013); p. 851 – 857;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia