The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 62458-96-2, name is 7-Benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4(3H)-one. This compound has unique chemical properties. The synthetic route is as follows. name: 7-Benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4(3H)-one
31-A. 4-Oxo-4,5,6,8-tetrahydro-3H-pyrido[3,4-]pyrimidine-7-carboxylic acid tert-bxxty ester.; 7-Benzyl-5,6,7,8-tetrahydro-3H-pyrido[3,4-|pyrimidin-4-one (ref. Org. Proc. Res. Dev. 2005, 9, 80) (36.9 g, 153 mmol) and BOC anhydride (40.1 g, 184 mmol) are taken up in MeOH (600 mL). The vessel is purged with argon and palladium on carbon (10% w/w; wet) (5.0 g) is added. The contents are then stirred under a hydrogen atmosphere (1 arm) for 18 h. At that time the suspension is filtered over Celite and the resulting solution is concentrated to give the title compound. MS (ESI) m/z 252.0 (M+l).
With the rapid development of chemical substances, we look forward to future research findings about 62458-96-2.
Reference:
Patent; NOVARTIS AG; ARTMAN III, Gerald David; ELLIOTT, Jason Matthew; JI, Nan; LIU, Donglei; MA, Fupeng; MAINOLFI, Nello; MEREDITH, Erik; MIRANDA, Karl; POWERS, James J.; RAO, Chang; WO2010/66684; (2010); A2;,
Pyrimidine | C4H4N2 – PubChem,
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