Synthetic Route of 611-08-5, Adding some certain compound to certain chemical reactions, such as: 611-08-5, name is 5-Nitrouracil,molecular formula is C4H3N3O4, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 611-08-5.
Step 178.5: 1 ,3-Dimethyl-5-nitro-1 H-pyrimidine-2,4-dione The title compound was prepared in analogy to the procedure described for step 100.5 but using 5- nitrouracil. The reaction was performed at rt for 20 h. The reaction mixture was concentrated and triturated in CH2CI2. The resulting suspension was filtered and the solid was purified by flash chromatography (CH2CI2/MeOH, 94:6). tR: 0.41 min (LC-MS 2); ESI-MS: 186.1 [M+H]+ (LC-MS 2); Rf = 0.55 (CH2CI2/MeOH, 9:1 ).
According to the analysis of related databases, 611-08-5, the application of this compound in the production field has become more and more popular.
Reference:
Patent; NOVARTIS AG; FURET, Pascal; GUAGNANO, Vito; HOLZER, Philipp; KALLEN, Joerg; LIAO, Lv; MAH, Robert; MAO, Liang; MASUYA, Keiichi; SCHLAPBACH, Achim; STUTZ, Stefan; VAUPEL, Andrea; WO2013/111105; (2013); A1;,
Pyrimidine | C4H4N2 – PubChem,
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