Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 1005-37-4, name is 6-Chloro-N4-methylpyrimidine-2,4-diamine. This compound has unique chemical properties. The synthetic route is as follows. COA of Formula: C5H7ClN4
Example 2583-[2-am ino-6-(methylamino)pyrimidin-4-yl]-2-methylbenzonitrile.A mixture of 6-chloro-4-N-methylpyrimidine-2,4-diamine (24 mg, 0.15 mmol), (3-cyano-2-methylphenyl)boronic acid (29 mg, 0.18 mmol), potassium carbonate (41mg, 0.30 mmol) and palladium tetrakis(triphenylphosphine)palladium (0) (9 mg,0.008 mmol) in 1 ,4-dioxane (3 mL) and water (1 mL) was heated in a sealed tube at 900C overnight. The reaction mixture was concentrated and purified by preparative H PLC. LCMS [M+H] 240.
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Reference:
Patent; THOMAS HELLEDAYS STIFTELSE FOeR MEDICINSK FORSKNING; SCOBIE, Martin; HELLEDAY, Thomas; KOOLMEISTER, Tobias; JACQUES, Sylvain; DESROSES, Matthieu; JACQUES-CORDONNIER, Marie-Caroline; WO2014/84778; (2014); A1;,
Pyrimidine | C4H4N2 – PubChem,
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