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Application of 180869-36-7, Adding some certain compound to certain chemical reactions, such as: 180869-36-7, name is 4-(Dimethoxymethyl)-2-(methylthio)pyrimidine,molecular formula is C8H12N2O2S, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 180869-36-7.

(11-[2″{4″Pgperldinyloxy)-4-pyrjmi’dg?yf]ethyl}oxy)-2-th|opheStep A – 4-[Bis(methy.oxy)methy l]-2-(methylsuifonyl)pyrimidine4-[betais(methyfoxy)methyl]-2-(methyithlo)pyrimldme (US Patent 6218537, 2001) (8.24 g, 46.1 mmo.) was dissolved s? 150 mL of DCM and cooled to 0 C with stirring. 3-Chloroperoxybenzoic acid (23.87 g, 70%, 98.8 rnmoi) was added in a single portion. The reaction was altowed to reach r? slowly, The reaction was stirred 2 h and quenched by the addition of 150 ml of 10% sodium sulfite solution. The mixture was poured into a separatory funnel and the layers were separated. The organic layer was washed with 150 mL of 10% Na2COs solution (2X) and brine (IX). The organic layer was dried over ^IgSO4, filtered, and concentrated in vacuo. Purification by Hash chromatography afforded 10.25 g (98%) of the title compound. 1H NMR (400 IVlHz8 CDCb) S 8.96 (d, J- 4.9 Hz1 1 H), 778 (d , J^- 4.9 Hz, 1 H), 5.34 (s, 1 H), 3.48 (s, 6H), 3.38 (s, 3H).

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 180869-36-7, 4-(Dimethoxymethyl)-2-(methylthio)pyrimidine, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; SMITHKLINE BEECHAM CORPORATION; WO2007/143456; (2007); A2;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia