Related Products of 42965-55-9, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 42965-55-9, name is 5,6-Diaminopyrimidine-2,4(1H,3H)-dione sulfate. This compound has unique chemical properties. The synthetic route is as follows.
Example 72: 8-CycIopentyI-l-isobutyI-2-(2-methyI-pyridin-3-yIoxy)-l,7-dihydro- urin-6-one:; Step 1: 2,6-DichIoro-8-cyclopentyl-7H-purine:; A mixture of 5,6-diamino-lH-pyrimidine-2,4-dione sulphate (lOg, 70.42 mmol) and cyclopentanecarboxylic acid (8.02g, 70.42 mmol) was taken in POCI3 and stirred at reflux temperature for 3 days under inert conditions. Reaction mixture wasconcentrated and quenched with water and extracted with ethyl acetate. Ethyl acetate layer was washed with brine and water, dried over anhydrous sodium sulphate and concentrated. Residue obtained was purified by coloumn chromatography to provide 2,6-dichloro-8-cyclopentyl-7H-purine (3.5 g, 20 %) as brown solid.’HNMR(400MHz, CDC13): delta 1.25-1.81 (m, 2H); 1.85-1.93 (m, 2H); 1.98-2.07 (m, 2H); 2.20-2.25 (m, 2H); 3.42-3.45 (m, 1H); 1 1.50 (s, 1H).
According to the analysis of related databases, 42965-55-9, the application of this compound in the production field has become more and more popular.
Reference:
Patent; ADVINUS THERAPEUTICS PRIVATE LIMITED; RAMDAS, Vidya; KOUL, Summon; BASU, Sujay; WAMAN, Yogesh; SHEJUL, Yogesh; BARAWKAR, Dinesh; PALLE, Venkata Poornapragnacharyulu; WO2011/55391; (2011); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia