9/24/21 News Sources of common compounds: 4316-98-7

According to the analysis of related databases, 4316-98-7, the application of this compound in the production field has become more and more popular.

Electric Literature of 4316-98-7, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 4316-98-7, name is 6-Chloro-4,5-diaminopyrimidine. This compound has unique chemical properties. The synthetic route is as follows.

To a mixture of 6-chloro-pyrimidine-4,5-diamine (188 mg, 1.31 mmol), 1,3-dichloro-2-isothiocyanato-benzene (266 mg, 1.31 mmol), and CH3CN (5 mL) was added iPr2NEt (337 mg, 2.62 mmol) at rt. The mixture was heated to 90 C. in a sealed tube. After 12 h, the reaction was cooled and purified by preparative reverse-phase HPLC to afford the title compound as a colorless solid (80 mg, 20%). MS (ESI): mass calcd. for C11H6Cl3N5, 312.9; m/z found, 314.0 [M+H]+. 1H NMR ((CD3)2SO): 9.90 (br s, 1H), 8.39 (s, 1H), 7.62 (d, J=8.1 Hz, 2H), 7.43 (t, J=8.1 Hz, 1H).

According to the analysis of related databases, 4316-98-7, the application of this compound in the production field has become more and more popular.

Reference:
Patent; Lebsack, Alec D.; US2009/156598; (2009); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia